A massive explosion rocked Kabul city at about 8.30am on Wednesday in rush hour traffic.
The explosion ripped through the diplomatic zone causing widespread damage.
Early indications are that explosives had been placed in a water tanker.
Ministry of Public Health officials said so far at least 60 people have been wounded. Not details yet on the death toll.
However, the Wazir Akbar Khan hospital confirmed that 90 wounded were transported to their hospital, as well as three dead.
TOLOnews journalist Sharif Amiri, who is reporting from the scene, said the explosion happened close to the German embassy and Roshan telecommunications company in downtown Kabul.
The exact target is not yet known.