As many as 200 school girls were poisoned in Sultan Razia high school in Kabul early Wednesday, local officials said.
The incident took place at about 10:00am in the 7th district of Kabul, as the students entered their classrooms.
Screaming, fatigue, stomach ache, and vomiting were of symptoms shown by the girls, the head of central hospitals of the Ministry of Public Health, Kabir Amiri, said.
The girls were taken to the Isteqlal and Ibni Sina hospitals for treatments.
The girls are aged between 8 and 22.
Meanwhile, the head of Ibni Sina hospital, Mohammad Tahir Furmuli, said that "nearly 200 students have been taken to the hospital for treatment."
Investigations have been started about the substance that poisoned the students, according to officials.
The Afghan Education Ministry also confirmed the report and said students were fine and feeling well.
"It happened today morning in Sultan Razia high school, while the students arrived and felt some smell. The students were immediately taken to the hospital," the Education Ministry spokesman, Amanullah Eman, said.
The students said that they were feeling bad while, the teachers had started the lessons.
"I was in the class and smelt something strange and then I had a headache and was taken to the hospital," said a student.
"I saw most of the students were in very bad condition and they were taken to the hospital," said another student.
The families of the students expressed concern about the incident and called on the government to punish those behind the poisoning.
No group has claimed responsibility for the incident.
It comes as, a week ago more than 59 female students from Bebee Mariam high school in
Taloqan the capital of northeastern Takhar province were apparently poisoned.
Last year, more than 120 school girls in Kapisa, 181 in Ghazni and Kabul, and 10109 in Khost, Bamyan, Takhar and Sar-e-Pul provinces were poisoned.